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Mifepristone + Misoprostol UsesMifepristone+Misoprostol is used for medical abortion.How Mifepristone + Misoprostol worksMifepristone + Misoprostol is a combination of two medicines: Mifepristone and Misoprostol, which causes abortion. Mifepristone blocks the effects of progesterone, a natural female hormone that is needed for the pregnancy to sustain. Without this hormone, the lining of the uterus (womb) breaks down as it does during a menstrual period and stops the growth of the pregnancy. Misoprostol increases contractions of the uterus to cause abortion.